UW Health is participating in a trial to test how artificial intelligence can help radiologists detect breast cancer earlier and more accurately.
The PRISM Trial (Pragmatic Randomized Trial of Artificial Intelligence for Screening Mammography) hopes to test how AI can help radiologists when looking at mammograms.
PRISM is the first randomized controlled trial for AI mammography in the United States, according to Dr. Christoph Lee, a professor and vice chair of research for the Department of Radiology at the UW School of Medicine Public Health.
The first phase will take place over the next two years, with around 50,000 women in Wisconsin taking part in the trial as they complete their regular screenings.

Randomly, half of the patients will have an FDA-approved AI tool assist a radiologist in analyzing the data, while the other half will go through routine screening without the AI tool.
“We just don’t know enough about that human-AI interaction and how that will change the human perception and assessment. And this trial is going to help answer that question,” explained Dr. Lee.
After the first two years, they hope to have 400,000 women enrolled in the trial throughout the country. Lee says they will then be able to look into the algorithm and compare whether or not the AI tool helps the general population.
UW Health is one of seven sites across the country taking part in the trial.

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